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Rule-based Anomaly Pattern Detection for Detecting Disease Outbreaks (2002)

Weng-Keen Wong Andrew Moore Gregory Cooper Michael Wagner

Tags

AD-trees, Applications, Association Rules, Biosurveillance, Efficient Statistical Algorithms, WSARE

Abstract

This paper presents an algorithm for performing early detection of disease outbreaks by searching a database of emergency department cases for anomalous patterns. Traditional techniques for anomaly detection are unsatisfactory for this problem because they identify individual data points that are rare due to particular combinations of features. When applied to our scenario, these traditional algorithms discover isolated outliers of particularly strange events, such as someone accidentally shooting their ear, that are not indicative of a new outbreak. Instead, we would like to detect anomalous patterns. These patterns are groups with specific characteristics whose recent pattern of illness is anomalous relative to historical patterns. We propose using a rule-based anomaly detection algorithm that characterizes each anomalous pattern with a rule. The significance of each rule is carefully evaluated using Fisher's Exact Test and a randomization test. Our algorithm is compared against a standard detection algorithm by measuring the number of false positives and the timeliness of detection. Simulated data, produced by a simulator that creates the effects of an epidemic on a city, is used for evaluation. The results indicate that our algorithm has significantly better detection times for common significance thresholds while having a slightly higher false positive rate.

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Approximate BibTeX Entry

@inproceedings{wong-rule,
    Year = {2002},
    Publisher = {MIT Press},
    Booktitle = {Proceedings of the 18th National Conference on Artificial Intelligence},
    Note = {Also available online from http://www.cs.cmu.edu/$sim$awm/antiterror},
    Author = {Weng-Keen Wong Andrew Moore Gregory Cooper Michael Wagner},
    Title = {Rule-based Anomaly Pattern Detection for Detecting Disease Outbreaks}
}

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